Side effects of Crestor(rosuvastatin)


Crestor is an HMG-CoA inhibitor, also known as a statin. Crestor is used along with dietary changes to lower your low-density lipoprotein(LDL) or  “bad” cholesterol. Drugs in this class help treat high cholesterol by blocking a substance your liver needs to make cholesterol. They also work with your liver to break down the cholesterol in your blood. This drug can help prevent heart disease, heart attack, and stroke in some people. However, sometimes it causes unwanted side effects. Learn what they are and tips to ease or stop them. Crestor which is the brand name for rosuvastatin.

Crestor uses

Read the patient information leaflet if available from your pharmacist before you start taking rosuvastatin and each time you get a refill. If you have any questions, ask your doctor and pharmacist. Take this medication by mouth with or without as directed by your doctor, usually once daily. If you are taking the capsule form of medication, swallow the whole capsule. Do not crush the capsule. If you have difficulty swallowing the capsule read and follow the manufacturer’s instructions for use leaflet. You may open carefully the capsule and sprinkle the contents on 1 teaspoonful of soft food. Swallow all of the mixture without chewing.

It is very important to continue to follow your doctor’s advice about diet and exercise.

Side effects

Rosuvastatin may create some common or serious side effects.

Common side effects

Common side effects can include:

1. Feeling sick(nausea)

2. Stomach pain

3. Headache

4. Weak or dizzy

5. Constipation

6. Protein in your pee(urine)

7. Memory loss and confusion

8. Muscle pain

If the advice on how to cop does not help and any of these side effects bother you or do not go away, keep taking the medicine, but tell your doctor and pharmacist. They may recommend trying an alternative statin

Serious side effects

Serious side effects are rare and happen in less than 1 in 1,000 people. The following side effects are serious and require immediate attention:

Muscle breakdown(rhabdomyolysis)

Rhabdomyolysis is a breakdown of the muscles attached to your bones. It can be serious and can lead to severe kidney damage from the buildup of protein in the muscle tissue that is processed through your kidneys. The risk increases to 65 years or older. Patients with kidney impairment are also at an increased risk for myalgia. Talk with your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you have a fever or feel more tired than usual while you take this drug. Your doctor may have you stopping to take the drug.

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 Liver damage

Liver disease can also cause severe side effects. Liver injury is rare but it happens, it usually occurs two to four months into Crestor therapy. Your doctor should do blood tests to check your liver before you start taking Crestor. Call your doctor right away if you have any of the following symptoms of liver disease:

         Dark urine

         Unusual tiredness or weakness

         Loss of appetite

         The yellow of your skin or the whites of your eyes

         Pain in your upper abdomen

Hemorrhagic strokes

Crestor prevents the recurrence of ischemic stroke. but statins may increase the risk of hemorrhagic strokes. Scientists have not determined the exact cause. However, the general hypothesis is that cholesterol may somehow be important to cell wall integrity. In other words, low cholesterol levels may increase the risk of blood vessel rupture.


You may also feel fatigued when taking either of these drugs. According to a study funded by the National Institutes of Health, women have a substantial risk of fatigue when taking statins. This risk was greater in women who took simvastatin compared with women who took other statins. Crestor was not included in the study, however.

Memory impairment

Cases of cognitive impairment have been reported in patients using Crestor and other statins.

Memory impairment may be reversible by temporarily discontinuing Crestor. Reports included cases of memory loss, forgetfulness, amnesia, memory impairment, and confusion. The recovery time averages about three weeks. Patients should not stop taking a prescription drug without consulting a doctor.

Reducing side effects

If you do have side effects, you can take steps to help relieve them or even make them go away. Talk with your doctor about the following actions: 

Consult with your doctor:

Make sure your doctor believes Crestor is the best medication for you, given your symptoms and healthy history.

Take a short break:

Stopping Crestor for a short time can help you decide whether your aches and pains are due to the medication or something else. Talk with your doctor before you stop taking your medication, however.

Change your dose:

Lowering your dose may reduce some of your side effects. But it may also reduce some of the cholesterol-lowering drugs. Your doctors need to approve these dosage changes before you try them.

Dosage and strength

Both Crestor and Simvastatin come in a range of strengths. Crestor is a more lot potent. For example, 40mg is a high dose of simvastatin, but you would get that same dose of Crestor in about 10mg. Always take the dosage your doctor prescribes for you for each drug.

Talk with your doctor

Simvastatin and Crestor are both drugs and your doctor may prescribe for high cholesterol. Each person has different health risks. These risks influence decisions about which statin might be best. Tell your doctor if you take several other drugs or have heavy kidney disease. If you already take a statin and have side effects such as muscle pain or dark urine discuss with your doctor as well. They can check your lab work adjust your treatment and help to prevent problems.

I am a medical student. I researched Crestor after researching I feel that this drug is useful for cholesterol-lowering. 

Writer name:

                    Ifrah Khalid

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