Vabysmo’s generic name is FARICIMAB-SVOA. It is used to treat certain serious eye conditions (such as wet age-related macular degeneration, and diabetic macular edema). It is used to help prevent decreased vision and blindness. Faricimab works by slowing the growth of abnormal new blood vessels in the eye and decreasing leakage from these blood vessels.
This medication is prepared and given by injection into the affected eye by a healthcare professional. You have leaky blood vessels in a part of your eye called the macula. The macula is an area at the back of your eye that allows you to see shapes, colors, and details. When the blood vessels leak, this makes the macula swell. The swelling can damage the macula and lead to loss of vision. This tends to get worse over time.
Vabysmo does the following in the macula:
Slows the growth of abnormal blood vessels
Reduces leaking from blood vessels, which help to:
Reduce swelling, which improves your vision
Reduce further damage to the macula, which helps slow vision loss
The most common adverse effect associated with the use of Vabysmo was conjunctival hemorrhage. Endophthalmitis and retinal detachments may occur following intravitreal injections. Patients should be instructed to report any symptoms suggestive of endophthalmitis or retinal detachment without delay, to permit prompt and appropriate management. Increases in intraocular pressure have been seen within 60 minutes of an intravitreal injection. There is a potential risk of arterial thromboembolic events (ATEs) associated with VEGF inhibition.
Mild side effects
Mild side effects of Vabysmo that have been reported include:
Temporary vision problems, such as blurry vision
Bleeding on the surface of your eye where the needle has entered, causing a red spot on the white part of your eye
Floaters (dots or squiggly lines that move) in your vision
Eye discomfort or pain
Eye irritation or itching
A sensation of having something in your eye
Mild allergic reaction
Serious side effects
Serious side effects of Vabysmo that have been reported include:
Temporary increase in pressure inside your eye
Infection inside your eye
Blood clots that may cause a heart attack and stroke
Severe allergic reaction
Before you take this medication tell your doctor or pharmacist. If you feel any side effects ask your doctor right away. If you are pregnant or plan to become pregnant. You should not become pregnant while using Faricimab. This may harm an unborn baby. Your doctor should order a pregnancy test before you start taking this medication. Consult your doctor or pharmacist.
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